Instone Nutrition

INSTONE is committed to bringing you the best that nutritional science has to offer. Our products are made from the highest quality sources derived from premium ingredients. As such, we have compiled a list of scientific resources and articles that allow to see for yourself why INSTONE is best in class and a leader in nutritional science.

Increases in Testosterone

Incledon T, The Chronic Effects of Androst-4-Ene-3,6,17-Trione on Endocrine Response in Resistance-Trained Men.

Prasad A, Mantzoros C, Beck F, Hess J, Brewer G. Zinc Status and Serum Testosterone Levels of Healthy Adults. 1996 Nutrition Vol. 12 (5) 344-8.

Costello L, et al. Evidence for a Zinc Uptake Transporter in Human Prostate Cancer Cells Which is Regulated by Prolactin and Testosterone. The Journal of Biological Chemistry. 1999 June 274 (25): 17499-17504.

Brilla L.R., et al. Effects of a Novel Zinc-Magnesium Formulation on Hormones and Strength. Journal of Exercise Physiologyonline. 2000 October, 3 (4) 26-36.

Rowland D, et al. A Review of Plant-Derived and Herbal Approaches to the Treatment of Sexual Dysfunctions. Journal of Sex & Marital Therapy. 2003, 29 (3): 185-205.

Decreased Estrogen Levels

Incledon T, The Chronic Effects of Androst-4-Ene-3,6,17-Trione on Endocrine Response in Resistance-Trained Men.

Promotion of healthy lipid levels

Incledon T, The Chronic Effects of Androst-4-Ene-3,6,17-Trione on Endocrine Response in Resistance-Trained Men.

Metabolic Enhancement

Dulloo AG, Geissler CA, Horton T, Collins A, Miller DS. Normal caffeine consumption: influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers. Am J Clin Nutr. 1989 Jan;49(1):44-50.

Hollands MA, Arch JR, Cawthorne MA. A simple apparatus for comparative measurements of energy expenditure in human subjects: the thermic effect of caffeine. Am J Clin Nutr. 1981 Oct;34(10):2291-4.

Acheson KJ, Maarkiewic B, Pittet P,. Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals. Am J Clin Nutr. 33: May 1980 989-997.

Dulloo AG, Duret C, Rohrer D, Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am J Clin Nutr. 1999, 70. 1040-5.

Thermogenesis

Hollands MA, Arch JR, Cawthorne MA. A simple apparatus for comparative measurements of energy expenditure in human subjects: the thermic effect of caffeine. Am J Clin Nutr. 1981 Oct;34(10):2291-4.

Astrup A, Toubro S, Cannon S, Hein P, Breum L, Madsen J . Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers. Am J Clin Nutr. 1990 May;51(5):759-67.

Bobyleva V, Bellei M, Kneer N, Lardy H. The Effects of the Ergosteroid 7-KETO™ DHEA on mitochondrial membrane potential: possible relationship to thermogenesis.

Marwah P, et al. Ergosteroids IV: Synthesis and Biological Activity of Steroid Glucuronosides.

Increased Fat Metabolism

Kao YH, Modulation of obesity by a green tea extract catechin. Am J Clin Nutr. 2000;72: 1232-41.

Acheson KJ, Maarkiewic B, Pittet P,. Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals. Am J Clin Nutr. 33: May 1980 989-997.

Douglas S. Kalman, Carlon M. Colker, Melissa A. Swain, Georgeann C. Torina, and Qiuhu Shi, A Randomized, Double-Blind, Placebo Controlled Study of 3-Acetyl-7-Oxo-Dehydroepiandrosterone in Healthy Overweight Adults

C Colker, M.D, G Torina, M Swain, D Kalman. Department of Medicine, Greenwich Hospital, Peak Wellness, Inc, Greenwich, CT 06830 Double-Blind, Placebo-Controlled, Randomized Clinical Trial Evaluating the Effects of Exercise Plus 3-Acetyl-7-oxo-dehydroepiandrosterone on Body Composition and the Endocrine System in Overweight Adults

Marwah P, et al. Ergosteroids IV: Synthesis and Biological Activity of Steroid Glucuronoids, Ethers and Alkylcarbonates. Steroids 2001; 66: 581-595.

Appetite Suppression

Quinlan PT, Lane J, Moore KL, Aspen J, Rycroft JA, O'Brien DC. The acute physiological and mood effects of tea and coffee: the role of caffeine level. Pharmacol Biochem Behav. 2000 May;66(1):19-28

Nehlig A, Daval JL, Debry G.Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects. Brain Res Brain Res Rev. 1992 May-Aug;17(2):139-70

Liao S. The Medicinal Action of Androgens and Green Tea Epigallocatechin Gallate. HKMJ 2001; 7(4): 369-374.

Liao, S (2001) The medicinal action of androgen and green tea epigallocatechin gallate. HKMJ 7(4): 369-374.

Kao, Y, Hiipakka, RA, Liao, S (2000) Modulation of Endocrine Systems and Food Intake by Green Tea Epigallocatechin Gallate Endocrinology 141(3): 980-987.

Increases in Energy

Poehlman ET. LaChance P, The effect of prior exercise and caffeine ingestin on metabolic rate and hormones in young adult males. Can J Physiol. Pharmacol. Vol 67, 1989

Graham TE, Spriet LL. Performance and metabolic responses to a high caffeine dose during prolonged exercise. J Appl Physiol. 1991 Dec;71(6):2292-8.

Bell Dg, McLellan TM, Exercise Endurance 1, 3 and 6 h after caffeine ingestion in caffeine users and nonusers. J Apply Physiol. 2002 Oct;93(4):1227-34.

Increased Performance & Endurance

Musa A, et al. Effect of Rhodiola rosea and Rhodiola crenulata root extracts on ATP content in Muscle Mitochondria. Experimental Biology and Medicine. 2003; 136 (12) 664-666.

Baranov V.M. Experimental Trials of Herbal Adaptogen Effect on the Quality of Operator Activity, Mental and Professional Working Capacity. 1994; 2-40.

Brown R. Rhodiola rosea A Phytomedicinal Overview, 2002; 56: 40-52.

Bogatova R, et al. Evaluation of the Effect of a Single Dose of a Phytoadaptogen on the Working Capacity of Human Subjects During Prolonged Isolation. 1997; 31(4): 51-54.

Ramazanov Z. Rhodiola Rosea The Premier Adaptogen for Mental and Physical Health. 2003.